As Motionographer aptly puts it,

Director John Likens and FX Supervisor Tomas Slancik dissect existential collapse in Your Friends & Neighbors’ haunting opener, blending Jon Hamm’s live-action gravitas with a symphony of digital decay. […]

Shot across two days and polished by world-class VFX artists, the title sequence mirrors Hamm’s crumbling protagonist, juxtaposing his stoic performance against hyper-detailed destruction.