Mikons is "a new form of self-expression that connects people through visual symbols (personal tags)," and the site creators call their Mikon Machine (created using Director) "the most advanced drawing tool of its kind available on the Internet."
They plan to add color, text input, a product builder, and a store to enable artists to sell their designs.
Cumulate Draw offers a some similar capabilities but is done by leveraging the scripting engines built into modern Web browsers [Via]
If having humans in the loop gets you down, why not try a little tree art? British artist Tim Knowles attaches pens to the branches of various trees, letting them draw whatever the wind dictates. I’m having trouble getting the photos to appear in my browser, but here’s a link in case you have more luck.
Not out there enough for you? Okay, how about 50,000 rat neurons in a petri dish driving a robot arm in Australia, translating neural activity into drawings? Read all about it.